Washington University in St Louis Cooper Lab
Dept of Biochemistry & Molecular Biophysics
Washington University in St Louis
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Postal address
CB 8231
660 South Euclid Avenue
St. Louis, MO 63110
Shipping address
Dept. of Cell Biology
4523 Clayton Avenue
St. Louis, MO 63110
Telephone numbers
(314) 362-4606 Lab
(314) 362-0287 BMB Office
(314) 362-3964 CBP Office
Lab location
Room 2903
South Building
4577 McKinley Ave
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People in the Lab

Contact Form
John John
Marc Joanna
Olivia Patrick McConnell


Ben Benjamin
Lab Photos Lab Alumni
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  We may have opportunities for graduate students and postdoctoral fellows to join the lab. Send email to John Cooper via our Email Contact Form.
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Teaching Files

Lectures for Molecular Foundations of Medicine

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Posters from Meetings & Presentations

Cooper Lab General Poster 2016
ASCB 2015 - CARMIL2 (pdf)
Gordon Conf 2015 - CP Requires CPI-Motif(pdf)

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CARMIL Family Proteins as Multidomain Regulators of Actin-based Motility. Stark, B. C. et al. 2017. Mol Biol Cell 28:1713-1723.


TransEndoth Migration Collaborations:
Trojan Horse Transit Contributes to Blood-Brain Barrier Crossing of a Eukaryotic Pathogen. Santiago-Tirado, F. H. et al. 2017. mBio 8: e02183-16.
New in vitro method for assaying the migration of primary B cells using an endothelial monolayer as substrate. Stewart-Hutchinson, P. J. et al. 2017. J Leukoc Biol (in press).
Mst1 Kinase Regulates the Actin-Bundling Protein L-Plastin To Promote T Cell Migration. Xu, X. et al. 2016. J Immunol 197: 1683-91.
L-Plastin promotes podosome longevity and supports macrophage motility. Zhou, J. Y. et al. 2016. Mol Immunol 78: 79-88.


Actin-Regulator Feedback Interactions during Endocytosis. Xu et al. 2016. Biophys. J. 110:1430-1443.Online Journal.

CARMIL2 Vimentin

Cell Migration and Invadopodia Formation Require a Membrane-binding Domain of CARMIL2. Lanier et al. 2016. J Biol Chem.291:1076-1091. Online Journal.

CARMIL2 Vimentin

CARMIL2 is a Novel Molecular Connection between Vimentin and Actin Essential for Cell Invasion. Lanier et al. 2015. Mol Biol Cell.26:4577-4588. Online Journal.

MBoC Cover Image PDF.


Differential expression of CARMIL-family genes during zebrafish development. Stark & Cooper. 2015. Cytoskeleton.72:534-541. Online Journal.


CPI Motif Interaction is Necessary for Capping Protein Function in Cells. Edwards et al. 2015. Nature Comm. 6:8415. Online Journal.


Role of N-WASP in Endothelial Monolayer Formation and Integrity. Mooren et al. 2015. J Biol Chem 290:18796-805. Online Journal.